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Invitrogen
SNX3 Polyclonal Antibody
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FIGURE: 1 / 1
SNX3 Antibody (PA5-110410) in WB
Western blot analysis of SNX3 in extracts of various cell lines. Samples were incubated with SNX3 Polyclonal antibody (Product # PA5-110410) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-110410
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human SNX3 (NP_003786.1).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.74 mg/mL
Amount
74 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MAETVADTRR LITKPQNLND AYGPPSNFLE IDVSNPQTVG VGRGRFTTYE IRVKTNLPIF KLKESTVRRR YSDFEWLRSE LERESKVVVP PLPGKAFLRQ LPFRGDDGIF DDNFIEERKQ GLEQFINKVA GHPLAQNERC LHMFLQDEII DKSYTPSKIR HA
Target Information
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. A pseudogene of this gene is present on the sex chromosomes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: contains domain conserved in sorting proteins SNX1; Mvp1p; Vps5p; Grd19p; SNX 3A; SNX3; sorting nexin 3A; unnamed protein product
Gene Aliases: Grd19; MCOPS8; SDP3
UniProt ID: (Human) O60493, (Mouse) O70492, (Rat) Q5U211
Entrez Gene ID: (Human) 8724, (Mouse) 54198, (Rat) 684097
protein binding
phosphatidylinositol-5-phosphate binding
protein phosphatase binding
phosphatidylinositol-3-phosphate binding
phosphatidylinositol binding
phosphatidylinositol-4-phosphate binding
phosphatidylinositol-3,5-bisphosphate binding
phosphatidylinositol phosphate binding
retromer complex binding
heme biosynthetic process
response to bacterium
membrane invagination
positive regulation of neuron projection development
protein to membrane docking
regulation of Wnt signaling pathway
endocytic recycling
regulation of intracellular protein transport
transferrin transport
late endosome to Golgi transport
negative regulation of protein catabolic process
hemoglobin biosynthetic process
negative regulation of viral entry into host cell
negative regulation of phagocytosis
regulation of protein transport
negative regulation of protein transport
regulation of protein metabolic process
intralumenal vesicle formation
negative regulation of early endosome to late endosome transport
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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