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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
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Protein Aliases: alpha 8 connexin; connexin 50; Connexin-50; Cx50; Gap junction alpha-8 protein; gap junction membrane channel protein alpha 8; Lens fiber protein MP70; lens opacity 10
Gene Aliases: Aey5; Cnx50; Cx50; GJA8; Lop10
UniProt ID: (Mouse) P28236
Entrez Gene ID: (Rat) 29601, (Mouse) 14616
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