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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-113408
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SPARC-related modular calcium-binding protein 1 protein (277-382AA)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Secreted modular calcium-binding protein 1 (SMOC1) is a gene located on chromosome 14q24.2, encoding a member of the SPARC (Secreted Protein, Acidic, and Rich in Cysteine) family of matricellular proteins. SMOC1 is characterized by its multiple domains that facilitate calcium binding and interaction with various components of the extracellular matrix. This protein plays a crucial role in modulating cell-matrix interactions and signaling pathways involved in cellular adhesion, migration, and differentiation. SMOC1 is expressed in multiple tissues, including the eyes, limbs, and the central nervous system, and is essential for developmental processes such as angiogenesis and tissue formation. Mutations in SMOC1 have been linked to ocular conditions like anterior segment dysgenesis and microphthalmia, reflecting its significance in eye development. Current studies focus on the protein's broader implications in developmental disorders and its potential as a therapeutic target in diseases associated with extracellular matrix dysregulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Secreted modular calcium-binding protein 1; SMOC-1; SPARC-related modular calcium-binding protein 1
Gene Aliases: SMOC1
Entrez Gene ID: (Human) 64093
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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