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Invitrogen
APOBEC1 Polyclonal Antibody
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APOBEC1 Antibody (PA5-11429) in IHC (P)
Immunohistochemistry analysis of APOBEC1 in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with APOBEC1 polyclonal antibody (Product # PA5-11429) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-11429
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human Apobec1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.0 mg/mL
规格
800 µg
纯化类型
Ammonium sulfate precipitation, Size-exclusion - Dialysis
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor and APOBEC1 stimulating protein . This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: APO1; APOBEC-1; apolipoprotein B editing complex 1; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1; Apolipoprotein B mRNA-editing enzyme catalytic subunit 1; C->U-editing enzyme APOBEC-1; HEPR; mRNA(cytosine(6666)) deaminase 1
基因别名: APOBEC1; Cdar1
UniProt ID: (Mouse) P51908
Entrez Gene ID: (Mouse) 11810
catalytic activity
GTP cyclohydrolase activity
cytidine deaminase activity
cytosine deaminase activity
protein binding
tRNA-specific adenosine deaminase activity
zinc ion binding
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
AU-rich element binding
N-cyclopropylmelamine deaminase activity
N-cyclopropylammeline deaminase activity
N-cyclopropylammelide alkylamino hydrolase activity
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity
tRNA-specific adenosine-37 deaminase activity
archaeal-specific GTP cyclohydrolase activity
metal ion binding
tRNA-specific adenosine-34 deaminase activity
RNA processing factor
mRNA processing
response to osmotic stress
cytidine deamination
response to gamma radiation
cytidine to uridine editing
mRNA modification
regulation of cell proliferation
lipoprotein metabolic process
lipoprotein biosynthetic process
response to drug
lipoprotein transport
response to ethanol
mRNA stabilization
response to calcium ion
defense response to virus
DNA cytosine deamination
DNA demethylation
negative regulation of methylation-dependent chromatin silencing
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
