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Invitrogen
Fibrinogen alpha chain Polyclonal Antibody
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Fibrinogen alpha chain Antibody (PA5-114364) in WB
Western blot analysis of Fibrinogen alpha chain in the following samples: Lane 1: rat skeletal muscle tissue lysates, Lane 2: HEPG2 whole cell lysates. Samples consisting of 50 µg (reducing conditions) of protein was separated with 5-20% SDS-PAGE gel (70V, Stacking gel; 90V, Resolving gel; 2-3 hrs.), transferred to a Nitrocellulose membrane (150mA, 50-90 min) and washed with TBS-0.1% Tween (3 times, 5 minut... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-114364
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human FGA (687-727aa RTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVE).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat skeletal muscle tissue, HEPG2 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
Fibrinogen is a soluble protein found in blood plasma and is produced by the liver cells. The protein is a hexamer consisting of two sets of disulfide linked chains. Fibrinogen is essential for blood coagulation as the precursor of fibrin. It is converted to fibrin by the action of thrombin in the presence of calcium ions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fibrinogen a chain; Fibrinogen alpha; Fibrinogen alpha chain; Fibrinogen α chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; Fibrinogenα chain
基因别名: Ac1873; Fba5e; FGA
Entrez Gene ID: (Rat) 361969
acute-phase response
cell-matrix adhesion
signal transduction
blood coagulation
platelet activation
response to estradiol
response to genistein
positive regulation of heterotypic cell-cell adhesion
response to morphine
cellular protein complex assembly
innate immune response
positive regulation of vasoconstriction
positive regulation of exocytosis
response to cycloheximide
positive regulation of protein secretion
protein polymerization
response to calcium ion
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
cellular response to cytokine stimulus
cellular response to interleukin-6
cellular response to organic cyclic compound
blood coagulation, common pathway
positive regulation of peptide hormone secretion
liver regeneration
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
cellular response to granulocyte colony-stimulating factor
negative regulation of endothelial cell apoptotic process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
