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Invitrogen
Phospho-PP1 alpha (Thr320) Polyclonal Antibody
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图: 1 / 4
Phospho-PP1 alpha (Thr320) Antibody (PA5-114625) in ICC/IF
Immunocytochemistry analysis of Phospho-PP1 alpha (Thr320) in A549 cells (heat shock treatment). Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114625). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 c... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-114625
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PPP1CA around the phosphorylation site of Thr320.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of PPP1CA only when phosphorylated at Thr320.
靶标信息
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GADD34; MGC15877; MGC1674; PP-1A; protein phosphatase 1, catalytic subunit, alpha isoform; Protein phosphatase type 1 alpha, catalytic subunit; protein phosphatase-1d; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
基因别名: dism2; PPP1A; Ppp1c; PPP1CA
UniProt ID: (Mouse) P62137, (Rat) P62138
Entrez Gene ID: (Mouse) 19045, (Rat) 24668
carbohydrate metabolic process
glycogen metabolic process
regulation of glycogen biosynthetic process
regulation of glycogen catabolic process
regulation of translation
protein dephosphorylation
cell cycle
female meiotic division
cellular process
dephosphorylation
lung development
circadian regulation of gene expression
regulation of circadian rhythm
entrainment of circadian clock by photoperiod
rhythmic process
branching morphogenesis of an epithelial tube
cell division
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
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