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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of SGK2 only when phosphorylated at Thr253.
SGK2 is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Although little is known about the transcriptional regulation of SGK2, the protein has been shown to be phosphorylated and activated by 3 phosphoinositide dependent protein kinase 1 (PDK1), and to a lesser extent insulin like growth factor 1, in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Serine/threonine-protein kinase Sgk2; Serum/glucocorticoid-regulated kinase 2
基因别名: SGK2
UniProt ID: (Rat) Q8R4U9
Entrez Gene ID: (Rat) 171497