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Invitrogen
H2A.Zac pan-acetyl (K4,K7,K11,K13) Polyclonal Antibody
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H2A.Zac pan-acetyl (K4,K7,K11,K13) Antibody (PA5-114690) in IHC (P)
Immunohistochemistry analysis of H2A.Zac pan-acetyl (K4,K7,K11, K13) in human gastric cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114690) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-114690
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human H2AFZ(Accession P0C0S5), corresponding to amino acid residues M1-S21.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of Acetyl-H2A.Z only when acetylated at Lys4/7/11/13.
靶标信息
H2A.Zac pan-acetyl (K4,K7,K11,K13) is classified under histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: H2A histone family member Z; H2AFZ; H2AZ histone; histone (H2A.Z); unnamed protein product
基因别名: H2A.z; H2A.Z-1; H2A/z; H2AFZ; H2AZ
UniProt ID: (Human) P0C0S5
Entrez Gene ID: (Human) 3015
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