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Invitrogen
FGF8 Polyclonal Antibody
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图: 1 / 2
FGF8 Antibody (PA5-114734) in ICC/IF
Immunocytochemistry analysis of FGF8 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114734) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-114734
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FGF8(Accession P55075), corresponding to amino acid residues L152-T202.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total FGF8.
靶标信息
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIGF; androgen-induced; Androgen-induced growth factor; FGF; FGF-8; Fibroblast growth factor; Fibroblast growth factor 8; fibroblast growth factor 8 (androgen-induced); HBGF-8; Heparin-binding growth factor 8; MGC149376
基因别名: AIGF; Fgf-8; FGF8
UniProt ID: (Mouse) P37237
Entrez Gene ID: (Rat) 29349, (Mouse) 14179
MAPK cascade
patterning of blood vessels
metanephros development
branching involved in ureteric bud morphogenesis
organ induction
kidney development
mesonephros development
neural plate morphogenesis
heart looping
blood vessel remodeling
heart morphogenesis
outflow tract septum morphogenesis
outflow tract morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
apoptotic process
response to oxidative stress
determination of left/right symmetry
heart development
motor neuron axon guidance
mesodermal cell migration
positive regulation of cell proliferation
gonad development
fibroblast growth factor receptor signaling pathway
embryo development ending in birth or egg hatching
positive regulation of gene expression
response to organic cyclic compound
telencephalon development
pallium development
subpallium development
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
forebrain neuron development
central nervous system neuron development
signal transduction involved in regulation of gene expression
lung development
BMP signaling pathway
male genitalia development
thyroid gland development
otic vesicle formation
midbrain-hindbrain boundary development
dorsal/ventral axon guidance
embryonic heart tube development
limb morphogenesis
embryonic hindlimb morphogenesis
aorta morphogenesis
inner ear morphogenesis
odontogenesis
regulation of odontogenesis of dentin-containing tooth
response to drug
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
cell fate commitment
positive regulation of mitotic nuclear division
positive regulation of organ growth
generation of neurons
forebrain morphogenesis
positive chemotaxis
negative regulation of cardiac muscle tissue development
pharyngeal system development
canonical Wnt signaling pathway
corticotropin hormone secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
bone development
lung morphogenesis
branching involved in salivary gland morphogenesis
neuroepithelial cell differentiation
dopaminergic neuron differentiation
cell migration involved in mesendoderm migration
multicellular organism development
cell differentiation
positive regulation of cell division
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