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Invitrogen
Chromogranin C Polyclonal Antibody
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图: 1 / 6
Chromogranin C Antibody (PA5-115018) in ICC/IF
Immunocytochemistry analysis of Chromogranin C in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115018) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115018
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SCG2(Accession P13521), corresponding to amino acid residues K49-L99.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Chromogranin C.
靶标信息
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chromogranin C (Secretogranin II); Chromogranin-C; secretogranin 2; Secretogranin II; secretogranin II (chromogranin C); Secretogranin-2; SgII
基因别名: Chcg; CHGC; Scg-2; SCG2; SgII
UniProt ID: (Mouse) Q03517, (Rat) P10362
Entrez Gene ID: (Mouse) 20254, (Rat) 24765
MAPK cascade
angiogenesis
positive regulation of endothelial cell proliferation
intracellular signal transduction
eosinophil chemotaxis
positive chemotaxis
induction of positive chemotaxis
negative regulation of endothelial cell apoptotic process
negative regulation of extrinsic apoptotic signaling pathway
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