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FCER1G Antibody (PA5-115222) in ICC/IF
Immunocytochemistry analysis of FCER1G in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115222) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115222
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FCER1G(Accession P30273), corresponding to amino acid residues K52-Q86.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total FCER1G.
Target Information
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fc fragment of IgE receptor Ig; Fc fragment of IgE, high affinity I, receptor for; Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; Fc receptor gamma-chain; Fc receptor, IgE, high affinity I, gamma polypeptide; fc-epsilon RI-gamma; Fc-epsilon-receptor gamma-chain protein precursor; FcepsilonRI gamma chain; FcepsilonRIgamma; fceRI gamma; fcRgamma; gamma polypeptide; high affinity IgE receptor gamma subunit precursor; igE Fc receptor subunit gamma; immunoglobulin E receptor, high affinity, gamma chain; unnamed protein product
Gene Aliases: CD23; Fce1g; FcepsilonRI; FcR-gamma; FcR[g]; FCRG; FcRgamma; Ly-50
UniProt ID: (Human) P30273, (Rat) P20411, (Mouse) P20491
Entrez Gene ID: (Human) 2207, (Rat) 25441, (Mouse) 14127
positive regulation of type IIa hypersensitivity
positive regulation of type III hypersensitivity
positive regulation of type I hypersensitivity
neutrophil activation involved in immune response
T cell differentiation involved in immune response
Fc receptor mediated stimulatory signaling pathway
serotonin secretion by platelet
phagocytosis, engulfment
signal transduction
cell surface receptor signaling pathway
integrin-mediated signaling pathway
regulation of platelet activation
immunoglobulin mediated immune response
antigen processing and presentation of exogenous peptide antigen via MHC class II
osteoclast differentiation
neutrophil chemotaxis
receptor internalization
regulation of tumor necrosis factor production
positive regulation of interleukin-10 production
positive regulation of interleukin-2 production
positive regulation of interleukin-4 production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of mast cell cytokine production
negative regulation of mast cell apoptotic process
Fc-gamma receptor signaling pathway
Fc-epsilon receptor signaling pathway
interleukin-3-mediated signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I
defense response to bacterium
positive regulation of mast cell degranulation
innate immune response
mast cell activation
positive regulation of phagocytosis
regulation of immune response
positive regulation of immune response
positive regulation of T cell receptor signaling pathway
cellular response to low-density lipoprotein particle stimulus
protein localization to plasma membrane
Fc receptor-mediated immune complex endocytosis
positive regulation of protein localization to cell surface
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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