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Invitrogen
IL2RG Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115413
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human IL2RG(Accession P31785), corresponding to amino acid residues S53-S103.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total IL2RG.
靶标信息
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD132; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL2R gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); Interleukin-2 receptor subunit gamma; p64
基因别名: [g]c; Ab2-183; CD132; gamma(c); gc; IL2RG; p64
UniProt ID: (Mouse) P34902
Entrez Gene ID: (Rat) 140924, (Mouse) 16186
immune response
regulation of gene expression
positive regulation of gene expression
cytokine-mediated signaling pathway
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
positive regulation of T cell differentiation in thymus
positive regulation of B cell differentiation
positive regulation of lymphocyte differentiation
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