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Invitrogen
IDE Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115425
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human IDE(Accession P14735), corresponding to amino acid residues L97-T147.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Insulin degrading enzyme/IDE.
靶标信息
This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Abeta-degrading protease; FLJ35968; Insulin degrading enzyme; Insulin protease; Insulin-degrading enzyme; Insulinase; Insulysin
基因别名: 1300012G03Rik; 4833415K22Rik; AA675336; AI507533; IDE; INSDEGM
UniProt ID: (Rat) P35559
Entrez Gene ID: (Rat) 25700, (Mouse) 15925
beta-amyloid binding
glycoprotein binding
metalloendopeptidase activity
receptor binding
ATP binding
peptidase activity
zinc ion binding
ATPase activity
peptide hormone binding
beta-endorphin binding
peptide binding
protein homodimerization activity
ubiquitin binding
insulin binding
nucleotide binding
catalytic activity
metallopeptidase activity
hydrolase activity
metal ion binding
metalloprotease
proteolysis
determination of adult lifespan
bradykinin catabolic process
ubiquitin homeostasis
positive regulation of protein oligomerization
hormone catabolic process
peptide catabolic process
cellular protein catabolic process
negative regulation of proteolysis
beta-amyloid metabolic process
protein homooligomerization
protein homotetramerization
protein heterooligomerization
proteolysis involved in cellular protein catabolic process
insulin metabolic process
insulin catabolic process
metabolic process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
