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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total Macro H2A.2.
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Core histone macro-H2A.2; Histone macroH2A2; histone mH2A2; mH2A2
基因别名: H2AFY2; H2afy3; MACROH2A2; RGD1561371
UniProt ID: (Mouse) Q8CCK0
Entrez Gene ID: (Rat) 361844, (Mouse) 404634