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Invitrogen
RAB29 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115819
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RAB29(Accession O14966), corresponding to amino acid residues W51-R101.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total RAB7L1.
靶标信息
Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269; PubMed:22042847, ECO:0000269; PubMed:24788816}.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Rab-7-like protein 1; RAB7, member RAS oncogene family-like 1; Ras-related GTP-binding protein Rab29; Ras-related protein Rab-29; Ras-related protein Rab-7L1
基因别名: RAB29; RAB7L1
UniProt ID: (Rat) Q63481
Entrez Gene ID: (Mouse) 226422, (Rat) 171122
transport
intracellular protein transport
Golgi organization
small GTPase mediated signal transduction
protein transport
cell differentiation
melanosome organization
Rab protein signal transduction
retrograde transport, plasma membrane to Golgi
positive regulation of intracellular protein transport
ER to Golgi vesicle-mediated transport
metabolic process
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