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Invitrogen
RAMP1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115823
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RAMP1(Accession O60894), corresponding to amino acid residues C82-L132.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total RAMP1.
靶标信息
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1; MGC38240; receptor (calcitonin) activity modifying protein 1; Receptor activity-modifying protein 1
基因别名: 9130218E19Rik; RAMP1
UniProt ID: (Rat) Q9JJ74, (Mouse) Q9WTJ5
Entrez Gene ID: (Rat) 58965, (Mouse) 51801
angiogenesis
calcium ion transport
intracellular protein transport
signal transduction
G-protein coupled receptor signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
protein transport
positive regulation of cAMP biosynthetic process
receptor internalization
positive regulation of protein glycosylation
protein localization to plasma membrane
transport
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