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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total SEPT4.
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 4-Sep; Apoptosis-related protein in the TGF-beta signaling pathway; Arts; Bradeion beta; Brain protein H5; CE5B3 beta; Cell division control-related protein 2; cell division control-related protein 2b; expression gene 3 in rat visual cortex; expression gene 3-1 in rat visual cortex; hCDCREL-2; M-Septin; peanut-like 2; peanut-like 2 homolog; Peanut-like protein 2; septin H5; Septin-4
基因别名: ARTS; Bh5; C17orf47; EG3-1RVC; EG3RVC; Gm11492; hucep-7; OTTMUSG00000001265; Pnut12; PNUTL2; SEP4; SEPT4; SEPTIN4
UniProt ID: (Mouse) P28661, (Rat) A0A096MJN4
Entrez Gene ID: (Mouse) 18952, (Rat) 287606