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Invitrogen
Ferroportin Polyclonal Antibody
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Ferroportin Antibody (PA5-115915) in IHC (P)
Immunohistochemistry analysis of Ferroportin in human colorectal cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115915) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115915
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SLC40A1(Accession Q9NP59), corresponding to amino acid residues G12-A62.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SLC40A1.
靶标信息
SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAR1; Cell adhesion regulator; duodenal-specific; Ferroportin; ferroportin 1; Ferroportin-1; Iron-regulated transporter 1; Metal transporter protein 1; metal transporting protein 1; MTP1; polycythaemia; SLC11A3 iron transporter; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 39 (iron-regulated transporter), member 1; Solute carrier family 40 member 1
基因别名: Dusg; FPN; FPN1; Fpt1; IREG1; MSTP079; MTP; MTP1; Ol5; Pcm; SLC11A3; Slc39a1; SLC40A1
UniProt ID: (Mouse) Q9JHI9, (Rat) Q923U9
Entrez Gene ID: (Mouse) 53945, (Rat) 170840
lymphocyte homeostasis
endothelium development
transport
ion transport
iron ion transport
cellular iron ion homeostasis
regulation of transcription from RNA polymerase II promoter in response to iron
iron ion transmembrane transport
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
spleen development
iron ion homeostasis
spleen trabecula formation
multicellular organismal iron ion homeostasis
ferrous iron transmembrane transport
ferrous iron export
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