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Invitrogen
SLC7A5 Polyclonal Antibody
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图: 1 / 7
SLC7A5 Antibody (PA5-115916) in ICC/IF
Immunocytochemistry analysis of SLC7A5 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115916) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115916
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SLC7A5(Accession Q01650), corresponding to amino acid residues F399-V449.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SLC7A5.
靶标信息
Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.It is sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.It involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 4F2; 4F2 LC; 4F2 light chain; 4F2HC; 4T2HC; CD98 light chain; CD98HC; E16; hLAT1; Integral membrane protein E16; L-type amino acid transporter 1; Large neutral amino acids transporter small subunit 1; LAT1; MDU1; MP hLAT1; NACAE; Solute carrier family 7 member 5; y+ system cationic amino acid transporter
基因别名: 4F2LC; CD98LC; D0H16S474E; LAT1; MPE16; SLC7A5; TA1
UniProt ID: (Mouse) Q9Z127
Entrez Gene ID: (Mouse) 20539
amino acid transmembrane transport
transport
amino acid transport
multicellular organism development
nervous system development
L-amino acid transport
leucine transport
phenylalanine transport
tryptophan transport
cell differentiation
cation transmembrane transport
L-alpha-amino acid transmembrane transport
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