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Invitrogen
SOX11 Polyclonal Antibody
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SOX11 Antibody (PA5-115950) in ICC/IF
Immunocytochemistry analysis of SOX11 in 3T3 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115950) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115950
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SOX11(Accession P35716), corresponding to amino acid residues E378-D428.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SOX11.
靶标信息
This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: putative transcription factor; SOX-11; SRY; SRY (sex determining region Y)-box 11; SRY (sex-determining region Y)-box 11; SRY box 11; SRY-box 11; SRY-box containing gene 11; SRY-related HMG-box gene 11; unnamed protein product
基因别名: 1110038H03Rik; 6230403H02Rik; CSS9; end1; IDDMOH; MRD27
UniProt ID: (Human) P35716, (Mouse) Q7M6Y2, (Rat) P0C1G9
Entrez Gene ID: (Human) 6664, (Mouse) 20666, (Rat) 84046
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific double-stranded DNA binding
protein binding
negative regulation of transcription from RNA polymerase II promoter
kidney development
lens morphogenesis in camera-type eye
outflow tract morphogenesis
noradrenergic neuron differentiation
nervous system development
central nervous system development
brain development
positive regulation of gene expression
negative regulation of gene expression
positive regulation of cell development
oligodendrocyte development
glial cell proliferation
regulation of transforming growth factor beta receptor signaling pathway
spinal cord development
glial cell development
neuron differentiation
positive regulation of BMP signaling pathway
positive regulation of hippo signaling
skeletal muscle cell differentiation
positive regulation of neuron differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
sympathetic nervous system development
embryonic digestive tract morphogenesis
camera-type eye morphogenesis
embryonic skeletal system morphogenesis
negative regulation of lymphocyte proliferation
positive regulation of neurogenesis
hard palate development
soft palate development
negative regulation of glial cell proliferation
ventricular septum morphogenesis
lung morphogenesis
neuroepithelial cell differentiation
eyelid development in camera-type eye
cornea development in camera-type eye
closure of optic fissure
positive regulation of stem cell proliferation
negative regulation of transcription regulatory region DNA binding
positive regulation of lens epithelial cell proliferation
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