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Invitrogen
STRA8 Polyclonal Antibody
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图: 1 / 3
STRA8 Antibody (PA5-115977) in ICC/IF
Immunocytochemistry analysis of STRA8 in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115977). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115977
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human STRA8(Accession Q7Z7C7), corresponding to amino acid residues R205-S255.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Stra8.
靶标信息
Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. Can associate with DNA (possibly in an indirect manner), and in vitro can activate DNA transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: stimulated by retinoic acid 8; stimulated by retinoic acid gene 8; Stimulated by retinoic acid gene 8 protein; Stimulated by retinoic acid gene 8 protein homolog; stra8
基因别名: RGD1562852; STRA8
UniProt ID: (Mouse) P70278
Entrez Gene ID: (Mouse) 20899, (Rat) 500079
ovarian follicle development
DNA replication
female meiosis sister chromatid cohesion
synapsis
reciprocal meiotic recombination
spermatogenesis
fertilization
meiotic chromosome condensation
meiotic DNA replication checkpoint
meiotic DNA double-strand break formation
regulation of organ growth
oocyte development
meiotic cell cycle
cellular response to retinoic acid
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