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Invitrogen
THRAP5 Polyclonal Antibody
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THRAP5 Antibody (PA5-116039) in IHC (P)
Immunohistochemistry analysis of THRAP5 in mouse lung tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-116039) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116039
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MED16(Accession Q9Y2X0), corresponding to amino acid residues Q619-K669.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total THRAP5.
靶标信息
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DRIP92; Mediator complex subunit 16; Mediator of RNA polymerase II transcription subunit 16; thyroid hormone receptor associated protein 5; Thyroid hormone receptor-associated protein 5; thyroid hormone receptor-associated protein 95; Thyroid hormone receptor-associated protein complex 95 kDa component; thyroid hormone receptor-associated protein, 95-kD subunit; Trap95; Vitamin D3 receptor-interacting protein complex 92 kDa component
基因别名: 95kDa; A630083L04; DRIP92; MED16; THRAP5; Trap95
UniProt ID: (Mouse) Q6PGF3
Entrez Gene ID: (Rat) 299607, (Mouse) 216154
transcription initiation from RNA polymerase II promoter
biological_process
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of receptor activity
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
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