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Invitrogen
TNF beta Polyclonal Antibody
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图: 1 / 7
TNF beta Antibody (PA5-116055) in ICC/IF
Immunocytochemistry analysis of TNF beta in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-116055) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116055
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LTA(Accession P01374), corresponding to amino acid residues A48-S98.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total TNF beta.
靶标信息
TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DAMA-25N12.13; LT-alpha; lymphotoxin A; lymphotoxin alpha; lymphotoxin alpha (TNF superfamily, member 1); Lymphotoxin-alpha; TNF b; TNF beta; TNF β; TNF-beta; TNFbeta; TNFβ; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1
基因别名: hlb382; LT; LT-[a]; LT-alpha; LT[a]; LTA; LTalpha; Ltx; TNF-beta; TNFB; TNFSF1; Tnfsf1b
UniProt ID: (Mouse) P09225, (Rat) Q06332
Entrez Gene ID: (Mouse) 16992, (Rat) 25008
positive regulation of chronic inflammatory response to antigenic stimulus
positive regulation of humoral immune response mediated by circulating immunoglobulin
obsolete transformed cell apoptotic process
inflammatory response
immune response
humoral immune response
cell proliferation
positive regulation of cell proliferation
cellular process
positive regulation of interferon-gamma production
positive regulation of apoptotic process
negative regulation of growth of symbiont in host
negative regulation of fibroblast proliferation
lymph node development
defense response to Gram-positive bacterium
positive regulation of glial cell proliferation
response to hypoxia
response to nutrient
response to lipopolysaccharide
response to drug
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