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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity. Cleaves ASARM peptides between Ser and Glu or Asp residues. Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide. Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides. Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HYP; Metalloendopeptidase homolog PEX; Phosphate-regulating neutral endopeptidase PHEX; Vitamin D-resistant hypophosphatemic rickets protein; X-linked hypophosphatemia protein
基因别名: PEX; PHEX
Entrez Gene ID: (Human) 5251