Invitrogen

HIP1R Polyclonal Antibody

Name: HIP1R Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-116542
Availability: InStock

查看其他10个HIP1R抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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HIP1R Antibody (PA5-116542) in WB

Western blot analysis of HIP1R in extracts of various cell lines. Samples were incubated with HIP1R Polyclonal antibody (Product # PA5-116542) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image HIP1R Polyclonal Antibody

产品信息

PA5-116542

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human HIP1R (NP_0039501)

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.05 mg/mL

105 µg

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2901173

产品详细信息

Positive Samples: U-87MG, 293T, HeLa, Mouse brain, Mouse spleen, Mouse liver, Rat brain

Immunogen sequence: KPVVVIPEEA PEDEEPENLI EISTGPPAGE PVVVADLFDQ TFGPPNGSVK DDRDLQIESL KREVEMLRSE LEKIKLEAQR YIAQLKSQVN ALEGELEEQR KQKQKALVDN EQLRHELAQL RAAQLEGERS QGLREEAERK ASATEARYNK LKEKHSELVH VHAELLRKNA DTAKQLTVTQ QSQEEVARVK EQLAFQVEQV KRESELKLEE KSDQLEKLKR ELEAKAGELA RAQEALSHTE QSKSELSSRL DTLSAEKDAL SGAVRQREAD LLAAQSLVRE TEAALSREQQ RSSQEQGELQ G

靶标信息

Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。