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Invitrogen
MLLT1 Polyclonal Antibody
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MLLT1 Antibody (PA5-116821) in WB
Western blot analysis of MLLT1 in extracts of various cell lines. Samples were incubated with MLLT1 Polyclonal antibody (Product # PA5-116821) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116821
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.03 mg/mL
规格
203 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse thymus, Rat brain, Rat thymus
Immunogen sequence: KTSKPHKVTK EHRERPRKDS ESKSSSKELE REQAKSSKDT SRKLGEGRLP KEEKAPPPKA AFKEPKMALK ETKLESTSPK G
靶标信息
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Eleven-nineteen-leukeumia; leukemia-associated protein MLLT1; myeloid/lymphoid or mixed lineage leukemia translocation to 1 homolog; myeloid/lymphoid or mixed lineage-leukemia translocation to 1 homolog; myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog; Protein ENL; trithorax; YEATS domain-containing protein 1
基因别名: AA407901; BAM11; ENL; LTG19; MLLT1; YEATS1
Entrez Gene ID: (Rat) 301119, (Mouse) 64144
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