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Invitrogen
PPP2R1A/PPP2R2A/PPP2R1B Polyclonal Antibody
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PPP2R1A/PPP2R2A/PPP2R1B Antibody (PA5-116861) in WB
Western blot analysis of PPP2R1A/PPP2R2A/PPP2R1B in extracts of various cell lines. Samples were incubated with PPP2R1A/PPP2R2A/PPP2R1B Polyclonal antibody (Product # PA5-116861) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116861
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human PPP2R1A/PPP2R2A/PPP2R1BPPP2R1A (NP_0550402)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.02 mg/mL
规格
102 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: HeLa, HepG2, K-562, NIH/3T3, C6, Mouse liver, Mouse lung, Rat brain, Rat testis
Immunogen sequence: MAAADGDDSL YPIAVLIDEL RNEDVQLRLN SIKKLSTIAL ALGVERTRSE LLPFLTDTIY DEDEVLLALA EQLGTFTTLV GGPEYVHCLL PPLESLATVE ETVVRDKAVE SLRAISHEHS PSDLEAHFVP LVKRLAGGDW FTSRTSACGL FSVCYPRVSS A
靶标信息
Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.The B regulatory subunit might modulate substrate selectivity and catalytic activity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: medium tumor antigen-associated 61 KDA protein; PP2A; PP2a-Abeta; protein phosphatase PP2A regulatory/structural subunit A isoform beta; PPP2R1A; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2, regulatory subunit A, beta; protein phosphatase 2, regulatory subunit B, alpha; protein phosphatase 2, structural/regulatory subunit A, beta; protein phosphatase PP2A; serine/threonine protein phosphatase A subunit type 2A; testicular secretory protein Li 1; unnamed protein product
基因别名: 2410004D02Rik; 2410091N08Rik; 6330556D22Rik; B55; B55A; B55ALPHA; HJS2; mKIAA1541; MRD36; PP2A; PP2A-Aalpha; PP2A-Abeta; PP2AA; PP2AAALPHA; PR52A; PR55A; PR55alpha; PR65; PR65A; PR65B
UniProt ID: (Human) P30153, (Human) P30154, (Human) P63151, (Mouse) Q76MZ3, (Rat) Q4QQT4, (Mouse) Q7TNP2, (Mouse) Q6P1F6, (Rat) P36876
Entrez Gene ID: (Human) 5518, (Human) 5519, (Human) 5520, (Mouse) 51792, (Rat) 117281, (Rat) 315648, (Mouse) 73699, (Mouse) 71978, (Rat) 117104
phosphoprotein phosphatase activity
protein binding
protein phosphatase regulator activity
protein heterodimerization activity
protein antigen binding
macromolecular complex binding
tau protein binding
protein phosphatase 2A binding
enzyme-substrate adaptor activity
protein serine/threonine phosphatase activity
chromosome segregation
snRNA processing
regulation of transcription elongation from RNA polymerase II promoter
regulation of hippo signaling
negative regulation of hippo signaling
intracellular signal transduction
regulation of growth
T cell homeostasis
regulation of cell differentiation
spindle assembly
meiotic sister chromatid cohesion, centromeric
negative regulation of protein kinase B signaling
protein-containing complex assembly
RNA polymerase II transcription initiation surveillance
biological_process
apoptotic process involved in morphogenesis
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
female meiotic division
meiotic spindle elongation
mitotic sister chromatid separation
peptidyl-serine dephosphorylation
regulation of meiotic cell cycle process involved in oocyte maturation
protein dephosphorylation
response to morphine
regulation of chromosome segregation
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