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Invitrogen
RREB1 Polyclonal Antibody
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RREB1 Antibody (PA5-116933) in WB
Western blot analysis of RREB1 in extracts of various cell lines. Samples were incubated with RREB1 Polyclonal antibody (Product # PA5-116933) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116933
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.45 mg/mL
规格
145 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Jurkat, U-251MG, Rat lung
Immunogen sequence: ATPLPGDALD QKGFLALLGL QHTKDVRPAP AEEPLPDDNQ AIQLQTLKCQ LPQDPGCTNL LSLSPFEAAS LGGSLTVLPA TKDSIKHLSL QPFQKGFIIQ PDSSIVVKPI SGESAIELAD IQQILKMAAS A
靶标信息
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Finger protein in nuclear bodies; Raf-responsive zinc finger protein LZ321; Ras-responsive element-binding protein 1; RREB 1; RREB-1; Zep 1; Zep-1; Zep1; Zinc finger motif enhancer-binding protein 1
基因别名: FINB; RREB1
Entrez Gene ID: (Rat) 306873
negative regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell migration
positive regulation of mammary gland epithelial cell proliferation
negative regulation of transcription, DNA-templated
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of wound healing, spreading of epidermal cells
positive regulation of lamellipodium morphogenesis
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