Search
Invitrogen
Phospho-Caveolin 2 (Ser36) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 7
Phospho-Caveolin 2 (Ser36) Antibody (PA5-118636) in IHC (P)
Immunohistochemical analysis of Phospho-Caveolin 2 (Ser36) in Human lung cancer tissue using a Phospho-Caveolin 2 (Ser36) polyclonal antibody (Product # PA5-118636). The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was use... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-118636
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CAV2(Accession P51636), corresponding to amino acid residues around phosphorylated Ser36.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of Caveolin 2 only when phosphorylated at Ser36.
靶标信息
Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: caveolae; Caveolin-2; MGC12294; Phospho-CAV2
基因别名: AI447843; CAV2
UniProt ID: (Mouse) Q9WVC3, (Rat) Q2IBC5
Entrez Gene ID: (Mouse) 12390, (Rat) 363425
SNARE binding
protein kinase binding
syntaxin binding
protein binding, bridging
mitogen-activated protein kinase kinase kinase binding
D1 dopamine receptor binding
protein complex scaffold
protein homodimerization activity
protein heterodimerization activity
phosphoprotein binding
scaffold protein binding
protein binding
scaffold/adaptor protein
negative regulation of endothelial cell proliferation
positive regulation of endothelial cell proliferation
endocytosis
vesicle fusion
mitochondrion organization
endoplasmic reticulum organization
chemical synaptic transmission
negative regulation of cell proliferation
insulin receptor signaling pathway
vesicle organization
receptor-mediated endocytosis of virus by host cell
negative regulation of transforming growth factor beta receptor signaling pathway
positive regulation of MAPK cascade
positive regulation of GTPase activity
vesicle docking
skeletal muscle fiber development
positive regulation of peptidyl-tyrosine phosphorylation
protein oligomerization
positive regulation of dopamine receptor signaling pathway
caveola assembly
positive regulation of protein localization to nucleus
regulation of mitotic nuclear division
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
