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Invitrogen
Phospho-PRK1/PRK2 (Thr774, Thr816) Polyclonal Antibody
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Phospho-PRK1/PRK2 (Thr774, Thr816) Antibody (PA5-118729) in ICC/IF
Immunocytochemistry analysis of Phospho-PRK1/PRK2 (Thr774, Thr816) in A549 cells (H2O2 treatment). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-PRK1/PRK2 (Thr774, Thr816) polyclonal antibody (Product # PA5-118729) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugate... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-118729
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PKN1(Accession Q16512), corresponding to amino acid residues around phosphorylated Thr774.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of PRK1/2 only when phosphorylated at Thr774/816.
靶标信息
Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiolipin-activated protein kinase Pak2; p140 kinase; PAK-1; PKN gamma; Protease-activated kinase 1; protease-activated kinase 2; Protein kinase C-like 1; Protein kinase C-like 2; Protein kinase C-like PKN; protein kinase PKN; Protein kinase PKN-alpha; Protein-kinase C-related kinase 1; Protein-kinase C-related kinase 2; Serine-threonine protein kinase N; Serine/threonine-protein kinase N1; Serine/threonine-protein kinase N2
基因别名: PAK-1; Pak-2; PAK1; PKN; PKN1; PKN2; PRK1; PRK2; PRKCL1; PRKCL2
UniProt ID: (Rat) Q63433
Entrez Gene ID: (Rat) 29355, (Rat) 207122
chromatin binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein kinase C binding
ATP binding
GTP-Rho binding
ligand-dependent nuclear receptor transcription coactivator activity
histone kinase activity (H3-T11 specific)
histone binding
histone deacetylase binding
Rac GTPase binding
androgen receptor binding
kinase activity
poly(A) RNA binding
RNA polymerase binding
non-receptor serine/threonine protein kinase
B cell homeostasis
B cell apoptotic process
negative regulation of protein phosphorylation
regulation of germinal center formation
regulation of immunoglobulin production
renal system process
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epithelial cell migration
negative regulation of B cell proliferation
histone H3-T11 phosphorylation
spleen development
regulation of cell motility
regulation of transcription, DNA-templated
apoptotic process
cell adhesion
positive regulation of cytokinesis
apical junction assembly
positive regulation of viral genome replication
positive regulation of mitotic cell cycle
cell division
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