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Invitrogen
FKBP5 Polyclonal Antibody
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FKBP5 Antibody (PA5-119119) in WB
Western blot analysis of FKBP5 using FKBP5 Polyclonal Antibody (Product # PA5-119119) at a dilution of 2 µg/mL. Lane 1: 293T cell lysate; Lane 2: K562 cell lysate; Lane 3: Mouse Thymus lysate. Secondary antibody used is HRP-Goat anti-Rabbit IgG polyclonal antibody at a dilution of 0.2 µg/mL.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-119119
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein FK506 Binding Protein 5. The antigen corresponds to amino acid range 2-457 of the target protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
FKBP5 is a member of the immunophilin protein family. This family plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP5 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. The gene that encodes FKBP5 has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor-associated immunophilin; Androgen-regulated protein 6; EC 5.2.1.8; FF1 antigen; FK506-binding protein 5; FKBP-5; FKBP54; HSP90-binding immunophilin; p54; Peptidyl-prolyl cis-trans isomerase FKBP5; PPIase FKBP5; Rotamase
基因别名: AIG6; D17Ertd592e; Dit1; FKBP-5; FKBP5; FKBP51
UniProt ID: (Mouse) Q64378
Entrez Gene ID: (Mouse) 14229
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