Search
Invitrogen
SPTBN1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 2
SPTBN1 Antibody (PA5-119749) in WB
Western blot analysis of SPTBN1 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. SPTBN1 Polyclonal Antibody (Product # PA5-119749) at 1:500 was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature. Positive control: Lane 1: SW1990 cell lysate. Lane 2: PANC-1 cell lysate. Lane 3: Rat brain tissue lysate. Lane 4: Mouse brain tissue lysate. Lane 5: Mouse cerebellu... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-119749
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within human sptbn1 aa 2320-2364.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: SW1990 cell lysate, PANC-1 cell lysate, rat brain tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, rat kidney tissue, human liver carcinoma tissue, mouse brain tissue.
Subcellular Location: Cell membrane, Cytoplasm, Cytoskeleton, Membrane.
靶标信息
Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic. Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure. Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin. A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc. (e. g. beta-1 epsilon-1).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: beta fodrin; beta II spectrin-like (short form); Beta-II spectrin; beta-spectrin 2, non-erythrocytic; brain spectrin; bSPII-; cytoskeleton protein; Embryonic liver fodrin; embryonic liver fodrin beta chain; Fodrin beta chain; non-erythrocytic; non-erythroid spectrin beta; short form of beta II spectrin; spectrin beta 2; spectrin beta chain, brain 1; Spectrin beta chain, non-erythrocytic 1; spectrin G; Spectrin, non-erythroid beta chain 1
基因别名: 9930031C03Rik; AL033301; Elf; elf1; elf3; mKIAA4049; Spnb-2; Spnb1; Spnb2; SPTB2; SPTBN1
UniProt ID: (Mouse) Q62261
Entrez Gene ID: (Rat) 305614, (Mouse) 20742
mitotic cytokinesis
plasma membrane organization
common-partner SMAD protein phosphorylation
SMAD protein import into nucleus
Golgi to plasma membrane protein transport
membrane assembly
protein targeting to plasma membrane
actin filament capping
positive regulation of interleukin-2 secretion
regulation of protein localization to plasma membrane
positive regulation of protein localization to plasma membrane
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
