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Invitrogen
AP2 gamma Polyclonal Antibody
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AP2 gamma Antibody (PA5-121134) in WB
Western blot analysis of AP2 gamma in extracts of various cell lines. Samples were incubated with AP2 gamma Polyclonal antibody (Product # PA5-121134) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-121134
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TFAP2C (NP_003213.1).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.38 mg/mL
规格
38 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: HeLa, Mouse lung, Rat lung. The target is usually found in the following locations: Nucleus.
Immunogen sequence: NMLLAAQQLC KEFTELLSQD RTPHGTSRLA PVLETNIQNC LSHFSLITHG FGSQAICAAV SALQNYIKEA LIVIDKSYMN PGDQSPADSN KTLEKMEKHR K
靶标信息
The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activating enhancer binding protein 2 gamma; Activating enhancer-binding protein 2 gamma; activator protein 2 gamma; AP-2.2; AP2-gamma; stimulated by retinoic acid gene 2; Transcription factor AP-2 gamma; Transcription factor ERF-1
基因别名: AA409384; Ap-2.2; AP2-gamma; AP2gamma; Stra2; Tcfap2c; TFAP2C
UniProt ID: (Mouse) Q61312
Entrez Gene ID: (Rat) 362280, (Mouse) 21420
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
molecular_function
DNA binding
transcription factor activity, sequence-specific DNA binding
protein dimerization activity
protein binding
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
trophectodermal cell differentiation
hair follicle development
keratinocyte development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
biological_process
male gonad development
stem cell population maintenance
forebrain neuron fate commitment
cerebral cortex development
cell differentiation
germ-line stem cell population maintenance
somatic stem cell population maintenance
regulation of gene expression, epigenetic
regulation of cell proliferation
skin development
regulation of epidermis development
positive regulation of transcription from RNA polymerase II promoter
sebaceous gland development
anatomical structure development
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
epithelial cell proliferation involved in mammary gland duct elongation
transcription, DNA-templated
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