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Invitrogen
Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) Polyclonal Antibody
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Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) Antibody (PA5-121285) in WB
Western blot analysis of Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) in extracts of HeLa cells. Samples were incubated with Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) Polyclonal antibody (Product # PA5-121285) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. HeLa cells were treated by Pervanadate (1 nM) at 37°C for 30 minutes ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-121285
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: HeLa.
靶标信息
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BDNF/NT-3 growth factors receptor; gp140trk; GP145-TrkB; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; Neurotrophic tyrosine kinase receptor type 2; p140-TrkA; Trk-A; Trk-B; TRK1-transforming tyrosine kinase protein; TrkB tyrosine kinase; Tropomyosin-related kinase A; Tropomyosin-related kinase B; Tyrosine kinase receptor; Tyrosine kinase receptor A
基因别名: MTC; NTRK1; NTRK2; TRK; TRKA; TRKB
Entrez Gene ID: (Human) 4914, (Human) 4915
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