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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive test controls include: NIH/3T3.
AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AKT1 kinase; Akt1m protein; DKFZp434N0250; kinase Akt1; MGC99656; pan akt; PKB; PKB alpha; PKB beta; PKB gamma; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B; Protein kinase B alpha; Protein kinase B beta; Protein kinase B gamma; protein kinase B, beta; protein kinase B-alpha; Proto-oncogene c-Akt; RAC protein kinase beta; RAC-alpha serine/threonine-protein kinase; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; STK-2; Thymoma viral proto-oncogene
基因别名: 2410016A19Rik; AI851531; Akt; AKT1; AKT2; AKT3; AW554154; D930002M15Rik; Nmf350; PKB; PKB/Akt; PKBalpha; PKBbeta; PKBG; RAC
UniProt ID: (Mouse) P31750, (Mouse) Q60823, (Mouse) Q9WUA6
Entrez Gene ID: (Mouse) 11651, (Mouse) 11652, (Mouse) 23797