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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
HspBP1 is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. The ATPase domain of Hsp70 binds HspBP1 and upon binding, inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 (3) and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Heat shock protein; Heat shock protein-binding protein 1; HSP; Hsp70-binding protein 1; Hsp70-binding protein 2; hsp70-interacting protein; Hsp70-interacting protein 1; Hsp70-interacting protein 2; HspBP1; HspBP2; SPA ) binding protein, cytoplasmic cochaperone 1
基因别名: 1500019G21Rik; HSPBP; HSPBP1; PP1845
UniProt ID: (Mouse) Q99P31
Entrez Gene ID: (Pig) 100518376, (Bovine) 512757, (Mouse) 66245