Search

  • 联系我们
  • 货号直购

Invitrogen

DJ-1 Polyclonal Antibody

高级验证
2 篇参考文献
查看其他30个DJ-1抗体

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
DJ-1 Polyclonal Antibody

产品信息

PA5-13404

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:2,000
查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

1:10-1:50
查看1篇已发表文章 1篇已发表文章
产品规格

种属反应

Human, Mouse

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DJ-1
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

规格

800 µg

纯化类型

Ammonium sulfate precipitation, Size-exclusion - Dialysis

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2160112

产品详细信息

This antibody is predicted to react with bovine and zebrafish based on sequence homology.

靶标信息

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: CTA-215D11.1; DJ-1; early onset 7; FLJ27376; FLJ34360; FLJ92274; Maillard deglycase; Oncogene DJ1; OTTHUMP00000001350; OTTHUMP00000001351; PARK7 GENE; PARK7/DJ1; Parkinson disease protein 7; Parkinson disease protein 7 homolog; Parkinsonism-associated deglycase; protein deglycase DJ-1; Protein DJ-1; Protein/nucleic acid deglycase DJ-1; RNA-binding protein regulatory subunit

查看更多 收起

基因别名: DJ-1; Dj1; PARK7

查看更多 收起

UniProt ID: (Mouse) Q99LX0

查看更多 收起

Entrez Gene ID: (Mouse) 57320

查看更多 收起

功能
transcription coactivator activity RNA binding mRNA binding histone deacetylase activity receptor binding copper ion binding protein binding transcription factor binding peptidase activity protein-N-terminal asparagine amidohydrolase activity UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity CoA hydrolase activity superoxide dismutase copper chaperone activity oxidoreductase activity, acting on peroxide as acceptor hydrolase activity iprodione amidohydrolase activity (3,5-dichlorophenylurea)acetate amidohydrolase activity glyoxalase III activity enzyme binding kinase binding cytokine binding 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity didemethylisoproturon amidohydrolase activity N-isopropylacetanilide amidohydrolase activity N-cyclohexylformamide amidohydrolase activity 2-oxoglutaryl-CoA thioesterase activity 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity isonicotinic acid hydrazide hydrolase activity cis-aconitamide amidase activity gamma-N-formylaminovinylacetate hydrolase activity 3-isopropylbut-3-enoyl-CoA thioesterase activity tyrosine 3-monooxygenase activator activity L-dopa decarboxylase activator activity identical protein binding protein homodimerization activity N2-acetyl-L-lysine deacetylase activity O-succinylbenzoate synthase activity indoleacetamide hydrolase activity N-acetylcitrulline deacetylase activity small protein activating enzyme binding ubiquitin-like protein conjugating enzyme binding glutaryl-CoA hydrolase activity mercury ion binding N-acetylgalactosamine-6-phosphate deacetylase activity acyl-CoA hydrolase activity androgen receptor binding peroxiredoxin activity diacetylchitobiose deacetylase activity chitooligosaccharide deacetylase activity repressing transcription factor binding scaffold protein binding cupric ion binding cuprous ion binding ubiquitin-specific protease binding glyoxalase (glycolic acid-forming) activity
参与通路
negative regulation of protein phosphorylation synaptic transmission, dopaminergic negative regulation of protein kinase activity proteolysis protein deglycosylation autophagy inflammatory response response to oxidative stress mitochondrion organization single fertilization cell proliferation adult locomotory behavior detoxification of copper ion positive regulation of gene expression negative regulation of gene expression enzyme active site formation via L-cysteine sulfinic acid methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione lactate biosynthetic process negative regulation of protein ubiquitination negative regulation of protein binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of interleukin-8 production positive regulation of peptidyl-serine phosphorylation negative regulation of protein sumoylation cellular response to oxidative stress cellular response to reactive oxygen species cellular response to glyoxal negative regulation of protein catabolic process response to hydrogen peroxide hydrogen peroxide metabolic process negative regulation of apoptotic process regulation of neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of transcription from RNA polymerase II promoter glycolate biosynthetic process negative regulation of protein export from nucleus regulation of inflammatory response detoxification of mercury ion protein stabilization positive regulation of sequence-specific DNA binding transcription factor activity negative regulation of ubiquitin-protein transferase activity dopamine uptake involved in synaptic transmission regulation of mitochondrial membrane potential membrane depolarization oxidation-reduction process membrane hyperpolarization negative regulation of cell death regulation of androgen receptor signaling pathway cellular response to hydrogen peroxide positive regulation of protein homodimerization activity positive regulation of protein localization to nucleus negative regulation of neuron death positive regulation of superoxide dismutase activity negative regulation of protein acetylation positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of mitochondrial electron transport, NADH to ubiquinone negative regulation of protein K48-linked deubiquitination negative regulation of TRAIL-activated apoptotic signaling pathway positive regulation of pyrroline-5-carboxylate reductase activity positive regulation of tyrosine 3-monooxygenase activity positive regulation of dopamine biosynthetic process glyoxal catabolic process positive regulation of L-dopa biosynthetic process positive regulation of L-dopa decarboxylase activity negative regulation of oxidative stress-induced cell death negative regulation of oxidative stress-induced neuron death negative regulation of hydrogen peroxide-induced cell death negative regulation of hydrogen peroxide-induced neuron death negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway positive regulation of reactive oxygen species biosynthetic process negative regulation of ubiquitin-specific protease activity positive regulation of oxidative phosphorylation uncoupler activity positive regulation of transcription regulatory region DNA binding positive regulation of androgen receptor activity negative regulation of extrinsic apoptotic signaling pathway negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持