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Invitrogen
LKB1 Polyclonal Antibody
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图: 1 / 5
LKB1 Antibody (PA5-14072) in ICC/IF
Immunocytochemistry analysis of LKB1 in ZR-75-1 cells. Samples were incubated in LKB1 polyclonal antibody (Product # PA5-14072) followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-14072
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
200 µg
纯化类型
Ammonium sulfate precipitation, Size-exclusion - Dialysis
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with chicken, mouse, rat and Xenopus based on sequence homology.
靶标信息
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAMK group; CAMKL family; Liver kinase B1; LKB 1; LKB-1; LKB1; LKB1(S); Renal carcinoma antigen NY-REN-19; Serine/threonine-protein kinase STK11
基因别名: LKB1; PJS; STK11
Entrez Gene ID: (Human) 6794
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