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Invitrogen

Aquaporin 1 Polyclonal Antibody

View all (24) Aquaporin 1 antibodies

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Aquaporin 1 Polyclonal Antibody

Product Details

PA5-144123

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

Assay-dependent
-

Immunoprecipitation (IP)

1:200-1:2,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human Aquaporin-1 protein (220-269AA)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

4 mg/mL

Amount

100 µg

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% Proclin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3094034

Target Information

Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AQP 1; AQP CHIP; AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; Channel-like integral membrane protein of 28 kDa; CHIP 28; Colton blood group; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; MGC26324; Urine water channel; water channel protein for red blood cells and kidney proximal tubule

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Gene Aliases: AQP1; CHIP28

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UniProt ID: (Mouse) Q02013, (Rat) P29975

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Entrez Gene ID: (Mouse) 11826, (Rat) 25240

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Function(s)
transporter activity intracellular cGMP activated cation channel activity potassium channel activity water transmembrane transporter activity ammonium transmembrane transporter activity potassium ion transmembrane transporter activity glycerol transmembrane transporter activity water channel activity glycerol channel activity transmembrane transporter activity nitric oxide transmembrane transporter activity carbon dioxide transmembrane transporter activity ephrin receptor binding protein binding transporter
Process(es)
glomerular filtration renal water transport cGMP biosynthetic process transport potassium ion transport water transport cell volume homeostasis cellular water homeostasis positive regulation of lamellipodium assembly positive regulation of epithelial cell migration carbon dioxide transport organic cation transport ammonium transport glycerol transport sensory perception of pain cellular homeostasis water homeostasis nitric oxide transport positive regulation of cell migration establishment or maintenance of actin cytoskeleton polarity secretion by cell secretory granule organization cellular response to stress carbohydrate transmembrane transport cellular response to UV transepithelial water transport carbon dioxide transmembrane transport wound healing response to drug negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process lipid digestion positive regulation of angiogenesis positive regulation of saliva secretion positive regulation of fibroblast proliferation camera-type eye morphogenesis corticotropin secretion transmembrane transport renal water absorption cellular response to hydrogen peroxide cellular response to inorganic substance cellular response to mechanical stimulus cellular response to copper ion cellular response to mercury ion cellular response to retinoic acid cellular response to cAMP cellular response to hypoxia cellular response to salt stress cellular hyperosmotic response cellular response to dexamethasone stimulus cellular response to nitric oxide potassium ion transmembrane transport ammonium transmembrane transport maintenance of symbiont-containing vacuole by host cation transmembrane transport hyperosmotic response response to hormone lateral ventricle development pancreatic juice secretion cerebrospinal fluid secretion odontogenesis hyperosmotic salinity response response to estrogen multicellular organismal water homeostasis metanephric descending thin limb development metanephric proximal straight tubule development metanephric proximal convoluted tubule segment 2 development metanephric glomerulus vasculature development
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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