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Invitrogen
KDM6A Polyclonal Antibody
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FIGURE: 1 / 3
KDM6A Antibody (PA5-144680) in IHC (P)
Immunohistochemistry of KDM6A in paraffin-embedded mouse small intestine tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with KDM6A polyclonal antibody (Product # PA5-144680) with a dilution of 1:4,000 for 1 hour at roo... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-144680
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within human KDM6A aa 60-800.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive control: Hela cell lysate, NIH/3T3 cell lysate, human small intestine tissue, mouse small intestine tissue.
Predicted band size: 154 kDa
Subcellular Location: Nucleus.
Target Information
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4lysine (K)-specific demethylase 6A; [histone H3]-trimethyl-L-lysine(27) demethylase 6A; Histone demethylase UTX; Lysine-specific demethylase 6A; ubiquitously transcribed tetratricopeptide repeat gene, X chromosome; Ubiquitously transcribed TPR protein on the X chromosome; Ubiquitously transcribed X chromosome tetratricopeptide repeat protein; Ubiquitously-transcribed TPR protein on the X chromosome; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein
Gene Aliases: KDM6A; UTX
UniProt ID: (Mouse) O70546
Entrez Gene ID: (Mouse) 22289
sulfonate dioxygenase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin binding
protein binding
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
identical protein binding
DNA-N1-methyladenine dioxygenase activity
metal ion binding
dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
histone demethylase activity (H3-K27 specific)
chromatin/chromatin-binding, or -regulatory protein
in utero embryonic development
neural tube closure
heart morphogenesis
respiratory system process
heart development
regulation of gene expression
chromatin modification
neural tube development
somite rostral/caudal axis specification
multicellular organism growth
mesodermal cell differentiation
embryonic organ development
notochord morphogenesis
oxidation-reduction process
canonical Wnt signaling pathway
histone H3-K27 demethylation
cardiovascular system development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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