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Invitrogen
PPP3CB Polyclonal Antibody
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图: 1 / 6
PPP3CB Antibody (PA5-15581) in ICC/IF
Immunofluorescence analysis of PPP3CB was performed using 70% confluent log phase MCF7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with PPP3CB Polyclonal Antibody (Product # PA5-15581) at 5 µg/mL in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-15581
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PPP3CB
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2 mg/mL
规格
800 µg
纯化类型
Size-exclusion - Dialysis, Ammonium sulfate precipitation
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with mouse and rat based on sequence homology.
靶标信息
PPP3CB is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Calmodulin-dependent calcineurin A subunit beta isoform; CAM-PRP catalytic subunit; CNA beta; PP2BA beta; RP11-345K20.1; Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
基因别名: 1110063J16Rik; CALNA2; CALNB; CNA2; Cnab; CnAbeta; PPP3CB
UniProt ID: (Mouse) P48453
Entrez Gene ID: (Mouse) 19056
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
calcium-dependent protein serine/threonine phosphatase activity
calcium ion binding
protein binding
calmodulin binding
drug binding
hydrolase activity
enzyme binding
protein phosphatase 2B binding
calmodulin-dependent protein phosphatase activity
metal ion binding
protein heterodimerization activity
protein dimerization activity
protein phosphatase
negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
protein phosphorylation
protein dephosphorylation
response to stress
heart development
regulation of gene expression
dephosphorylation
calcium ion regulated exocytosis
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
cellular response to drug
positive regulation of insulin secretion involved in cellular response to glucose stimulus
T cell homeostasis
positive regulation of transcription from RNA polymerase II promoter
regulation of insulin secretion
positive regulation of NFAT protein import into nucleus
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