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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
It is not recommended to aliquot this antibody.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha-5; Macropain zeta chain; Multicatalytic endopeptidase complex zeta chain; proteasome alpha 5 subunit; Proteasome subunit alpha type-5; Proteasome subunit alpha-5; Proteasome zeta chain
Gene Aliases: PSMA5; ZETA
UniProt ID: (Mouse) Q9Z2U1
Entrez Gene ID: (Mouse) 26442, (Rat) 29672
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