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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with caveolin-2 or -3.
Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAV1; caveolae; caveolin 1, caveolae protein, 22kDa; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; Caveolin-1; HGNC:1527; OTTHUMP00000196475; variant a; variant b
基因别名: CAV; Cav-1; CAV1; Caveolin-1; wu:fc07c04
UniProt ID: (Pig) Q6RVA9, (Chicken) P35431, (Bovine) P79132, (Mouse) P49817
Entrez Gene ID: (Pig) 404693, (Chicken) 373996, (Bovine) 281040, (Mouse) 12389, (Rat) 25404, (Chinese hamster) 100753021, (Zebrafish) 323695