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Invitrogen
ARF1/ARF2/ARF3/ARF4 Polyclonal Antibody
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FIGURE: 1 / 3
ARF1/ARF2/ARF3/ARF4 Antibody (PA5-18627) in WB
Western blot analysis of ARF1/ARF2/ARF3/ARF4 using ARF1/ARF2/ARF3/ARF4 Polyclonal Antibody (Product # PA5-18627) (1 µg/mL) in staining of A431 (A) and (0.3 µg/mL) of HeLa (B) and MCF7 (C) cell lysate (35 µg protein in RIPA buffer). Detected by chemiluminescence.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-18627
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (EGLDWLSNQLRNQK) corresponding to the C-terminus amino acids of ARF1 (aa 168-181).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor 1; ADP-ribosylation factor 2; ADP-ribosylation factor 3; ADP-ribosylation factor 4; ADP-ribosylation factor 5; ADP-ribosylation factor 6; ARF; Liver regeneration-related protein LRRG202; pan ARF
Gene Aliases: 5430400P17Rik; AA407803; Ac1-253; AI788669; AI854770; ARF1; ARF2; ARF3; ARF4; ARF5; ARF6; AW496366
regulation of receptor internalization
transport
cellular copper ion homeostasis
actin filament organization
small GTPase mediated signal transduction
protein transport
vesicle-mediated transport
regulation of Arp2/3 complex-mediated actin nucleation
very-low-density lipoprotein particle assembly
positive regulation of catalytic activity
positive regulation of endocytosis
positive regulation of calcium ion-dependent exocytosis
positive regulation of protein secretion
Golgi to transport vesicle transport
long term synaptic depression
positive regulation of dendritic spine development
synaptic vesicle budding
dendritic spine organization
lysosomal membrane organization
positive regulation of sodium ion transmembrane transport
positive regulation of late endosome to lysosome transport
positive regulation of ER to Golgi vesicle-mediated transport
regulation of phospholipid metabolic process
protein ADP-ribosylation
epidermal growth factor receptor signaling pathway
brain development
cell migration
activation of phospholipase D activity
negative regulation of apoptotic process
apical protein localization
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of transcription from RNA polymerase II promoter
response to axon injury
protein localization to cilium
regulation of reactive oxygen species metabolic process
learning
dendritic spine development
liver development
cell cycle
nervous system development
cell differentiation
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
ruffle organization
myeloid cell apoptotic process
regulation of toll-like receptor 4 signaling pathway
protein localization to cell surface
regulation of Rac protein signal transduction
protein localization to endosome
cell division
regulation of filopodium assembly
regulation of dendritic spine development
positive regulation of establishment of protein localization to plasma membrane
establishment of epithelial cell polarity
hepatocyte apoptotic process
negative regulation of dendrite development
actin cytoskeleton organization
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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