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Invitrogen
IGF2BP2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-18865
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (KQQEQKYPQGVASQR) corresponding to the C-terminus amino acids of IGF2BP2 (aa 583-598).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with canine and mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
靶标信息
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; IGF2 mRNA-binding protein 2; Insulin-like growth factor 2 mRNA-binding protein 2; p62; VICKZ family member 2
基因别名: IGF2BP2; IMP2; VICKZ2
Entrez Gene ID: (Human) 10644
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