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Invitrogen
ATP1B1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-19199
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (KTEISFRPNDPKSYE) corresponding to the internal amino acids of ATP1B1 (aa 85-99).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine, canine, human and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
靶标信息
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC1798; Na+/K+ ATPase Beta; Na,K-ATPase beta 1 subunit; OTTHUMP00000032537; OTTHUMP00000032538; Sodium Potassium ATPase; sodium/potassium ATPase beta subunit; Sodium/potassium-dependent ATPase subunit beta-1; Sodium/potassium-transporting ATPase subunit beta-1
基因别名: Atp1b1; Atp4b; Atpb; Atpb-1; ATPBS; NKbeta1
UniProt ID: (Rat) P07340, (Mouse) P14094
Entrez Gene ID: (Rat) 25650, (Mouse) 11931
response to hypoxia
blastocyst development
potassium ion transport
sodium ion transport
cellular calcium ion homeostasis
cellular sodium ion homeostasis
cell adhesion
potassium ion import
regulation of gene expression
regulation of cardiac muscle contraction by calcium ion signaling
metal ion transport
cellular potassium ion homeostasis
positive regulation of ATPase activity
sodium ion export from cell
protein stabilization
relaxation of cardiac muscle
cardiac muscle contraction
protein localization to plasma membrane
membrane repolarization
positive regulation of potassium ion transmembrane transporter activity
regulation of calcium ion transmembrane transport
positive regulation of sodium ion export from cell
positive regulation of calcium:sodium antiporter activity
positive regulation of potassium ion import
positive regulation of defense response to virus by host
transport
ion transport
mitophagy in response to mitochondrial depolarization
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