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Invitrogen
HLA-DQA1/DQA2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-19388
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (QGLRSVGASRH) corresponding to the C-terminus amino acids of HLA-DQA2 (aa 241-251).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DC-1 alpha chain; DC-alpha; DQ alpha; DQ alpha 2; DX alpha chain; HLA class II histocompatibility antigen DQ alpha chain; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; HLA DQ-alpha; HLA-DQ alpha chain; HLA-DQA1; HLA-DQA2; human leukocyte antigen DQA1/DRA; MHC class I antigen; MHC class II antigen; MHC class II antigen DQA1; MHC class II DQ alpha chain; MHC class II DQ-alpha protein; MHC class II DQA1; MHC class II DQA2; MHC class II HLA-D alpha glycoprotein; MHC class II HLA-DQ-alpha-1; MHC class II protein; MHC DQ alpha protein precursor; MHC HLA-DQ alpha; MHC HLA-DQ-alpha chain precursor old gene name 'HLA-DQA'; MHC HLA-DQ-alpha precursor; MHC HLA-DQA1-alpha protein; unnamed protein product
Gene Aliases: CELIAC1; DC-alpha; DQ-A1; DQA1; DX-ALPHA; HLA-DCA; HLA-DQA; HLA-DQA1*; HLA-DXA; HLADQA2
UniProt ID: (Human) P01909, (Human) P01906
Entrez Gene ID: (Human) 3117, (Human) 3118
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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