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Invitrogen
SUFU Polyclonal Antibody
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SUFU Antibody (PA5-19555) in WB
Western blot was performed using Anti-SUFU Polyclonal Antibody (Product # PA5-19555) and a 53 kDa band corresponding to SUFU was observed in all the tested cell models. Modified whole cell lysate (1% SDS) (30 µg lysate) of DU 145 (Lane 1), SH-SY5Y (Lane 2), PANC-1 (Lane 3), U-2 OS (Lane 4), A-431 (Lane 5) and HeLa (Lane 6) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # I... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-19555
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human Suppressor of Fused.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with rat, chicken and dog based on sequence homology.
靶标信息
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OTTHUMP00000020377; OTTHUMP00000020378; OTTHUMP00000020379; RP11-47A8.1; Suppressor of fused homolog
基因别名: Su(fu); Sufu
UniProt ID: (Mouse) Q9Z0P7
Entrez Gene ID: (Mouse) 24069
negative regulation of transcription from RNA polymerase II promoter
neural tube closure
heart looping
determination of left/right symmetry
spinal cord dorsal/ventral patterning
smoothened signaling pathway involved in ventral spinal cord interneuron specification
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
cytoplasmic sequestering of transcription factor
skin development
negative regulation of smoothened signaling pathway
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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