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Invitrogen
TNFRSF11B Polyclonal Antibody
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TNFRSF11B Antibody (PA5-19841) in WB
Western blot analysis of human neuroblastoma cell line whole cell lysate using Product # PA5-19841, Osteoprotegerin primary antibody at a dilution of 1 µg/mL (lane 1). Staining of K562 whole cell lysate at a dilution of 1 µg/mL (lane 2). Blot treated with a secondary HRP-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:3000.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-19841
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 200 - 300 Osteoprotegerin.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.9 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
For Western Blot, this antibody has non-specific bands at 105 kDa and 14 kDa.
This antibody is predicted to react with mouse, sheep, cow and pig based on sequence homology.
靶标信息
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MGC29565; Osteoprotegerin; soluble OPG; soluble Osteoprotegerin; sOPG; Tumor necrosis factor receptor superfamily member 11B
基因别名: Opg; Tnfrsf11b
UniProt ID: (Rat) O08727
Entrez Gene ID: (Rat) 25341
apoptotic process
signal transduction
response to nutrient
response to inorganic substance
extracellular matrix organization
response to magnesium ion
negative regulation of odontogenesis of dentin-containing tooth
response to drug
response to estrogen
negative regulation of bone resorption
response to arsenic-containing substance
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