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Invitrogen
NSE2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-20962
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide near the carboxy terminus of human MMS21.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is 293 cell lysate.
PA5-20962 can be used with blocking peptide PEP-1076.
靶标信息
This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 SUMO-protein ligase NSE2; E3 SUMO-protein transferase NSE2; FLJ32440; MMS21 homolog; Non-SMC element 2 homolog; Non-structural maintenance of chromosomes element 2 homolog
基因别名: 1110014D18Rik; AI661537; Mms21; Nsmce2; RGD1305156
UniProt ID: (Mouse) Q91VT1, (Rat) Q4V8A0
Entrez Gene ID: (Mouse) 68501, (Rat) 299957
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
SUMO transferase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA repair
DNA recombination
cellular response to DNA damage stimulus
cell cycle
mitotic nuclear division
positive regulation of maintenance of mitotic sister chromatid cohesion
positive regulation of mitotic metaphase/anaphase transition
cell division
cellular senescence
double-strand break repair via nonhomologous end joining
protein sumoylation
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